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After a degree in chemistry, Chris Busby worked in research for the Wellcome Foundation applying spectroscopic and analytical methods to chemical pharmacology and molecular drug interactions. He discontinued doctoral research in spectroscopy at Queen Mary College, London, following a dispute over ethics and returned to Burroughs Wellcome. He later researched Raman spectro-electrochemistry at the University of Kent, gaining a PhD. Since 1987, he has developed his interests in the health effects of ionizing radiation and developed the 'Second Event Theory' which distinguishes between hazards from external and internal irradiation. He is scientific secretary of the European Committee on Radiation Risk in Brussels and also national speaker on Science and Technology for the UK Green Party. As member of the International Society for Environment Epidemiology, he was invited to Iraq and Kosovo to investigate the health effects of depleted uranium. He has also given presentations on depleted uranium to the Royal Society and to the European Parliament. He is a member of the UK Ministry of Defence Oversight Committee on Depleted Uranium. He has identified childhood leukemia clusters around the Sellafield nuclear reactor, though his methodology has been disputed.<ref>Leukaemia incidence in Welsh children linked with low level radiation—making sense of some erroneous results published in the media</ref>
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